Gene information
Official symbol HAND2
Official full name heart and neural crest derivatives expressed 2
Gene type protein-coding gene
Chromosome4q34.1
Alias symboldHand; Thing2; Hed; bHLHa26
Gene familyBasic helix-loop-helix proteins
Resources
Entrez Gene 9464
HGNC HGNC:4808
Ensembl ENSG00000164107
Vega OTTHUMG00000160775
UCSC uc003ith.2
GO terms: 96 records
GO Description Category LogP Number of genes Detail
GO:0001216 DNA-binding transcription activator activity GO Molecular Functions -9.83829980 29 More
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific GO Molecular Functions -9.92639238 29 More
GO:0001501 skeletal system development GO Biological Processes -17.2073293 69 More
GO:0001525 angiogenesis GO Biological Processes -32.8794581 74 More
GO:0001568 blood vessel development GO Biological Processes -43.2646440 106 More
GO:0001667 ameboidal-type cell migration GO Biological Processes -17.0771232 40 More
GO:0001701 in utero embryonic development GO Biological Processes -8.76987260 44 More
GO:0001755 neural crest cell migration GO Biological Processes -8.06132628 15 More
GO:0001944 vasculature development GO Biological Processes -42.3240404 107 More
GO:0001947 heart looping GO Biological Processes -3.55523796 10 More
GO:0002009 morphogenesis of an epithelium GO Biological Processes -21.4354199 71 More
GO:0002520 immune system development GO Biological Processes -15.2957169 80 More
GO:0003007 heart morphogenesis GO Biological Processes -18.8519524 49 More
GO:0003143 embryonic heart tube morphogenesis GO Biological Processes -5.28631749 13 More
GO:0003151 outflow tract morphogenesis GO Biological Processes -7.88412825 17 More
GO:0003205 cardiac chamber development GO Biological Processes -16.2154327 37 More
GO:0003206 cardiac chamber morphogenesis GO Biological Processes -17.7982686 34 More
GO:0003231 cardiac ventricle development GO Biological Processes -15.0525208 31 More
GO:0005667 transcription regulator complex GO Cellular Components -7.37095162 26 More
GO:0007368 determination of left/right symmetry GO Biological Processes -1.76169613 11 More
GO:0007389 pattern specification process GO Biological Processes -10.9656233 30 More
GO:0007422 peripheral nervous system development GO Biological Processes -2.97285105 6 More
GO:0007423 sensory organ development GO Biological Processes -8.10586983 29 More
GO:0007507 heart development GO Biological Processes -29.3002557 91 More
GO:0007610 behavior GO Biological Processes -18.1916656 76 More
GO:0008134 transcription factor binding GO Molecular Functions -5.50998540 50 More
GO:0008283 cell population proliferation GO Biological Processes -17.2298624 68 More
GO:0009792 embryo development ending in birth or egg hatching GO Biological Processes -12.9988944 72 More
GO:0009799 specification of symmetry GO Biological Processes -2.36583162 13 More
GO:0009855 determination of bilateral symmetry GO Biological Processes -1.98243681 12 More
GO:0010611 regulation of cardiac muscle hypertrophy GO Biological Processes -13.5611908 22 More
GO:0010656 negative regulation of muscle cell apoptotic process GO Biological Processes -14.6475350 20 More
GO:0010660 regulation of muscle cell apoptotic process GO Biological Processes -26.1774267 35 More
GO:0010662 regulation of striated muscle cell apoptotic process GO Biological Processes -17.3771355 22 More
GO:0010665 regulation of cardiac muscle cell apoptotic process GO Biological Processes -17.8825743 22 More
GO:0014032 neural crest cell development GO Biological Processes -11.9399165 15 More
GO:0014033 neural crest cell differentiation GO Biological Processes -12.2997127 24 More
GO:0014743 regulation of muscle hypertrophy GO Biological Processes -14.1608908 23 More
GO:0030326 embryonic limb morphogenesis GO Biological Processes -4.09609747 9 More
GO:0034103 regulation of tissue remodeling GO Biological Processes -21.5631413 32 More
GO:0035050 embryonic heart tube development GO Biological Processes -8.08177140 18 More
GO:0035051 cardiocyte differentiation GO Biological Processes -18.7205561 33 More
GO:0035107 appendage morphogenesis GO Biological Processes -3.51424431 9 More
GO:0035108 limb morphogenesis GO Biological Processes -3.51424431 9 More
GO:0035113 embryonic appendage morphogenesis GO Biological Processes -4.09609747 9 More
GO:0035239 tube morphogenesis GO Biological Processes -44.2569269 123 More
GO:0042733 embryonic digit morphogenesis GO Biological Processes -2.75160215 5 More
GO:0042803 protein homodimerization activity GO Molecular Functions -14.2815375 77 More
GO:0043009 chordate embryonic development GO Biological Processes -11.8113315 68 More
GO:0043388 positive regulation of DNA binding GO Biological Processes -12.0675836 19 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0043433 negative regulation of DNA-binding transcription factor activity GO Biological Processes -10.6964949 32 More
GO:0043502 regulation of muscle adaptation GO Biological Processes -16.8828965 29 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045667 regulation of osteoblast differentiation GO Biological Processes -10.7517956 27 More
GO:0045668 negative regulation of osteoblast differentiation GO Biological Processes -3.60984508 9 More
GO:0048483 autonomic nervous system development GO Biological Processes -4.59833472 10 More
GO:0048514 blood vessel morphogenesis GO Biological Processes -39.8784810 93 More
GO:0048534 hematopoietic or lymphoid organ development GO Biological Processes -16.4041704 79 More
GO:0048538 thymus development GO Biological Processes -2.59334716 7 More
GO:0048562 embryonic organ morphogenesis GO Biological Processes -8.59880895 37 More
GO:0048568 embryonic organ development GO Biological Processes -17.1204114 64 More
GO:0048598 embryonic morphogenesis GO Biological Processes -22.1253699 83 More
GO:0048706 embryonic skeletal system development GO Biological Processes -2.56739645 13 More
GO:0048729 tissue morphogenesis GO Biological Processes -31.7796969 96 More
GO:0048732 gland development GO Biological Processes -26.3979320 74 More
GO:0048736 appendage development GO Biological Processes -3.44031493 10 More
GO:0048762 mesenchymal cell differentiation GO Biological Processes -16.1250183 37 More
GO:0048844 artery morphogenesis GO Biological Processes -13.4119116 22 More
GO:0048863 stem cell differentiation GO Biological Processes -16.2106470 36 More
GO:0048864 stem cell development GO Biological Processes -12.7283120 16 More
GO:0051090 regulation of DNA-binding transcription factor activity GO Biological Processes -25.8933515 78 More
GO:0051099 positive regulation of binding GO Biological Processes -11.1715489 31 More
GO:0051101 regulation of DNA binding GO Biological Processes -9.69427751 24 More
GO:0060021 roof of mouth development GO Biological Processes -2.59996800 6 More
GO:0060039 pericardium development GO Biological Processes -4.03573428 6 More
GO:0060173 limb development GO Biological Processes -3.44031493 10 More
GO:0060485 mesenchyme development GO Biological Processes -18.0238 46 More
GO:0060562 epithelial tube morphogenesis GO Biological Processes -17.7630248 53 More
GO:0060840 artery development GO Biological Processes -12.7697342 25 More
GO:0060973 cell migration involved in heart development GO Biological Processes -7.86308931 9 More
GO:0060976 coronary vasculature development GO Biological Processes -7.60302561 13 More
GO:0060977 coronary vasculature morphogenesis GO Biological Processes -6.32323278 8 More
GO:0061371 determination of heart left/right asymmetry GO Biological Processes -3.33317104 10 More
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding GO Molecular Functions -8.00802452 40 More
GO:0070372 regulation of ERK1 and ERK2 cascade GO Biological Processes -38.4320790 79 More
GO:0070374 positive regulation of ERK1 and ERK2 cascade GO Biological Processes -34.9831828 64 More
GO:0070888 E-box binding GO Molecular Functions -5.33490415 11 More
GO:0071300 cellular response to retinoic acid GO Biological Processes -4.69230219 12 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0090257 regulation of muscle system process GO Biological Processes -33.9441291 67 More
GO:0090497 mesenchymal cell migration GO Biological Processes -8.76593708 16 More
GO:0140297 DNA-binding transcription factor binding GO Molecular Functions -6.94737226 46 More
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
cg02774439 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
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